“Pushing Boundaries” by Harsha Mahabaleshwar (LKCMedicine) 1st Place


NTU Optical Bio-Imaging Centre (NOBIC) provides expertise in optical imaging and microscopy to researchers at Lee Kong Chian School of Medicine (LKCMedicine) and Singapore Centre for Environmental Life Sciences Engineering (SCELSE) at Nanyang Technological University, Singapore (NTU). Our team consists of physicists, chemists and engineers who together cover a broad range of expertise relevant to optical imaging in life and biomedical sciences, including the design and development of customised imaging systems, advanced imaging experiments or image processing and analysis. Our activities can be loosely divided into two domains (with a lot of overlap between them):

Imaging facilities operation and user support:

Research and development in optical imaging methods and instrumentation:

The research and development activities are centered around NOBIC Imaging Research Laboratory and the adjacent prototyping workshop, where a variety of custom optomechanical parts can be manufactured. 

We welcome collaboration with researchers and industrial partners. Do not hesitate to contact us if you think our expertise in optical imaging can help you to solve your scientific questions. Visit our GitHub page for details of our designs and solutions and for our collection of FIJI/Image J macros written for our microscopy facilities users.

Our Expertise

Instrumentation for Optical Imaging & (Micro)spectroscopy
Instrument Control Software Development & Image Analysis;
Microscopy Techniques, Applications & Sample Preparation

The research laboratory and the adjacent prototyping workshop form the focal point (pun intended) of NOBIC. This is where research into novel optical imaging modalities as well as building and testing of custom imaging instrumentation takes place. Check out our current research projects to see what we are working on here.

The laboratory also houses a prototype of NOBIC 2-photon microscope and an OCT system in a room ready for live-animal imaging.
The laboratory is equipped with:

-  3 large and 2 smaller optical tables
-  a glove box for clean assembly
-  3D printer
-  inverted epifluorescence microscope and a stereo-microscope
-  space, tools and components to build optical systems.

Prototyping Workshop

This is where precision manufacturing of custom (not only) optomechanical parts takes place. The in-house manufacturing capabilities allow us to build custom imaging instruments that are as compact, robust and easy to use, as you would expect from a commercial product.

We can do:

-  precision CNC machining (Haas Super Mini Mill 2, Tormach 15L Slant-PRO Lathe) 3D printing
-  electronics assembly
-  ...